O059 A study in Physiological Activation Responses to Posture Shifts in Sleep and The Impact of Supine Avoidance Alarms

Abstract Introduction This study assessed the frequency and duration of arousal responses associated with posture shifts during sleep time taken to resume following versus without a supine-avoidance alarm. Method Sleep shift outcomes baseline in-home (Embletta MPR plus an inactive alarm device) subsequent after 6-8 weeks treatment were examined in 66 patients supine-predominant OSA. A technician blinded supine-treatment data scored each study, including (3-15 ≥15-sec EEG changes). All lasting >5 sec identified from supine-alarm device recordings. sustained (≥30 sec) commencing established nights for (within -30 +3 shift) shift. Results The population was 62.1% males mean±SD age 52.8±11.9 years, BMI 31.9.4±7.8 kg/m², AHI 18.0±9.9 /hr (supine AHI=40.2±38.8 /h). From total 418 (baseline) vs 283 (supine-avoidance) (median [IQR] 6[3-10] 6[3-9] per patient), majority [342/418 244/283; 91[75-100] 100[84-100]%) arousal, followed by 0.5 [0.0 1.0] min before resumed, no difference supine-alarm. Conclusion Posture are mostly brief prior any alarm, which supine avoidance effectively discourages positioning minimal disturbance resumption sleep.